Hi Peter, thanks for the info!
Whether you can or not will depend on the capabilities of 00:00.0. Some have registers to block decoding for integrated devices. Sometimes they are documented. Sometimes not.
I've found a register to do what I want: D0F0x7C IOC Configuration Control bit 0 : ForceIntGfxDisable: internal graphics disable. Read-write. Setting this bit disables the internal graphics and the HD Audio Controller.
and it works :)