I checked the libftdi again and could not find any hint why this should be used.
Furhtermore I checked D2XX_Programmer's_Guide from FTDI and could not find any such function (https://www.ftdichip.com/Support/Documents/ProgramGuides/D2XX_Programmer's_Guide(FT_000071).pdf).

So may be the easiest and cleanest way is to set it to 4096 or to not set it at all (and use the libfdti default which is again 4096)?

Is there any argument to stay with setting the chunksize lower than 4096? (again as mentioned before: I chose 280 as there might has been any reason to set it lower than 4096. But if no one has an idea why, I would opt to set it to 4096).

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